KMID : 0363220080460050670
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Korean Journal of Dermatology 2008 Volume.46 No. 5 p.670 ~ p.673
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A Case of Piloleiomyoma Arising in a BCG Vaccination Site
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Kim Sung-Woo
Choi Woo-Seok Kang Yoo-Seok Lee Un-Ha Park Hyun-Su Jang Sang-Jai
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Abstract
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BCG is a live attenuated vaccine derived from Mycobacterium bovis. It can give rise to several cutaneous complications
including benign and malignant tumors. There are many reports about tumors arising in vaccination sites, especially those of small pox and BCG vaccinations. Reported tumors are basal cell carcinoma, dermatofibroma, melanoma, pilomatricoma and so on. Piloleiomyoma is a rare soft tissue tumor arising from arrector pili muscles. Clinically, piloleiomyomas appear as firm dermal papules and nodules with skin colored, pink, or reddish-brown surfaces. We experienced a case of piloleiomyma arising in a BCG vaccination site, which has not been reported in previous literature. Although several hypotheses have been propsed, there are no identified causes of leiomyoma. Trauma by the vaccination, persistent inflammation, wound healing process, or antigenic stimulation of the innoculation agent could be the possible causes in this case. (Korean J Dermatol 2008;46(5):670¡673)
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KEYWORD
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BCG vaccination, Complications, Piloleiomyoma
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